What is TremorStim?
TremorStim is a bioelectric stimulator with specific precise bioelectric signaling sequences for controlling essential tremors and other similar neurodegenerative disorders applied non-invasively. This is achieved in particular with controlled expression up regulation of specific proteins known to suppress essential tremors and the down regulation of other proteins known to trigger or extend essential proteins. The TremorStim peripheral stimulation product may be applied to the wrist, ankle, back or ear lobes or a combination thereof. The electrodes may be surface skin electrodes or electro acupuncture needles including micro needle patches.
The main TremorStim patent claims are highlighted below…
1. A method of treating a subject suffering from a neurodegenerative disorder, the method comprising:
applying a bioelectric signal to the subject that stimulates the expression and/or release of polypeptide(s) useful in the treatment of the neurodegenerative disorder.
Method of claim 1 applying a bioelectric signaling sequence to a cell that stimulates the cell to express and/or release EAAT2 polypeptide. wherein Lingo-1 is further down-regulated in the subject.
In addition, peripheral stimulation has been applied in the same perspective. Hence, the aim of TremorStim is to emerge forward with a non-invasive central and peripheral stimulation device alternative. TremorStim Plus is being developed for more serious Non-invasive brain stimulation techniques,direct current stimulation, are used to get essential tremors under control.
What is TremorStim Plus?
TremorStim Plus combines peripheral nerve stimulation with brain stimulation and in some cases focused ultrasound and/or pulsed light therapy for a more comprehensive treatment plan for severe advanced cases. Peripheral nerve stimulation in these cases may be applied to the wrist, ankle, back, ear lobes and head. Focused ultrasound will be applied to the head as well. Pulsed light therapy may be applied to the entire body including the head. In extremely severe cases this may be combined with infusions or injections of a mixed biologic composition comprised of a selection of or combination of any of these components; stem cells, amniotic fluid, PRF, Wharton’s Jelly, umbilical cord blood, selected exosomes, selected growth factors, micro RNA gel, nutrient hydrogel, oxygenated or other nanoparticles, selected alkaloids such as tetraharmine and micro matrix fragments.